# Esm (agent skill)

> Esm is an agent skill (a SKILL.md file) from K-Dense-AI/scientific-agent-skills. It uses the Biohub esm Python SDK for ESM3 protein generation, ESMC embeddings, and ESMFold2 all-atom folding. It works with Claude Code, Codex, Cursor, Gemini CLI and GitHub Copilot and has 47,813 GitHub stars across a repository of 7 listed skills.

Uses the Biohub esm Python SDK for ESM3 protein generation, ESMC embeddings, and ESMFold2 all-atom folding. Applies to local model inference and Biohub hosted clients, including former Forge workflows; distinguishes the separate legacy fair-esm distribution. Use for Biohub's esm SDK: ESM3 masked multimodal generation, ESMC sequence representations, and ESMFold2 all-atom prediction. The former Forge platform migrated to including ESM3; SDK class names still contain Forge.

## Key facts

| Fact | Value |
|---|---|
| Repository | https://github.com/K-Dense-AI/scientific-agent-skills |
| Skill path | skills/esm/SKILL.md |
| Skill name | esm |
| GitHub stars | 47,813 |
| Installs on skills.sh | not listed |
| License | MIT |
| Skills in repo | 7 |
| Plugin marketplace | no |
| Official | no |
| Works with | Claude Code, Codex, Cursor, Gemini CLI, GitHub Copilot |
| Category | Coding |
| Last commit | Oct 5, 2026 |

## When it triggers

- Uses the Biohub esm Python SDK for ESM3 protein generation, ESMC embeddings, and ESMFold2 all-atom folding.

## Add this skill

### Claude Code

```sh
git clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills.git
cp -r scientific-agent-skills/skills/esm ~/.claude/skills/esm   # personal, or .claude/skills in a project
```

In the Claude apps, zip the skill folder and upload it under Customize > Skills > + > Upload a skill (code execution must be on).

### ChatGPT / Codex

```sh
git clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills.git
cp -r scientific-agent-skills/skills/esm .agents/skills/esm   # repo; ~/.agents/skills for all projects
```

### Cursor

```sh
git clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills.git
cp -r scientific-agent-skills/skills/esm .cursor/skills/esm   # project; ~/.cursor/skills for all projects
```

Sources (checked 2026-10-07): https://code.claude.com/docs/en/skills, https://support.claude.com/en/articles/12512180-using-skills-in-claude, https://learn.chatgpt.com/docs/build-skills, https://cursor.com/docs/context/skills

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Canonical page: https://appsgit.com/skills/k-dense-ai-esm
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