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Esm

Esm is an agent skill (a SKILL.md file) from K-Dense-AI/scientific-agent-skills. It uses the Biohub esm Python SDK for ESM3 protein generation, ESMC embeddings, and ESMFold2 all-atom folding. It works with Claude Code, Codex, Cursor, Gemini CLI and GitHub Copilot and has 47,813 GitHub stars across a repository of 7 listed skills.

github.com/K-Dense-AI/scientific-agent-skills/skills/esm (opens in a new tab)

  • Multi-skill repo
  • Needs API key
  • Coding
  • Actively maintained
View on GitHub (opens in a new tab)

Add this skill

Claude

Claude Code loads skills from ~/.claude/skills/ (all projects) or .claude/skills/ (one project):

git clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills.git
cp -r scientific-agent-skills/skills/esm ~/.claude/skills/esm   # personal, or .claude/skills in a project

In the Claude apps, zip the esm folder and upload it under Customize > Skills > + > Upload a skill (code execution must be on).

ChatGPT / Codex

Codex reads skills from .agents/skills/ in a repo or ~/.agents/skills/ for every project:

git clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills.git
cp -r scientific-agent-skills/skills/esm .agents/skills/esm   # repo; ~/.agents/skills for all projects

Standalone skills also load in the ChatGPT desktop app.

Cursor

Cursor loads skills from .cursor/skills/ (or ~/.cursor/skills/) and also reads .claude/skills/:

git clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills.git
cp -r scientific-agent-skills/skills/esm .cursor/skills/esm   # project; ~/.cursor/skills for all projects

Source (checked Oct 7, 2026): code.claude.com/docs/en/skills (opens in a new tab), support.claude.com/en/articles/12512180-using-skills-in-claude (opens in a new tab), learn.chatgpt.com/docs/build-skills (opens in a new tab), cursor.com/docs/context/skills (opens in a new tab)

What this skill does

Uses the Biohub esm Python SDK for ESM3 protein generation, ESMC embeddings, and ESMFold2 all-atom folding. Applies to local model inference and Biohub hosted clients, including former Forge workflows; distinguishes the separate legacy fair-esm distribution. Use for Biohub's esm SDK: ESM3 masked multimodal generation, ESMC sequence representations, and ESMFold2 all-atom prediction. The former Forge platform migrated to including ESM3; SDK class names still contain Forge.

When it triggers

  • Uses the Biohub esm Python SDK for ESM3 protein generation, ESMC embeddings, and ESMFold2 all-atom folding.

More skills in K-Dense-AI/scientific-agent-skills

7 skills are listed from this repository.

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More coding skills

All Coding

FAQ

Esm FAQ

Still curious? Email info@appsgit.com.

What is the Esm skill?

Esm is an agent skill (a SKILL.md file) from K-Dense-AI/scientific-agent-skills. It uses the Biohub esm Python SDK for ESM3 protein generation, ESMC embeddings, and ESMFold2 all-atom folding. It works with Claude Code, Codex, Cursor, Gemini CLI and GitHub Copilot and has 47,813 GitHub stars across a repository of 7 listed skills. Its SKILL.md lives at github.com/K-Dense-AI/scientific-agent-skills/skills/esm.

How do I install the Esm skill?

Copy the esm folder (the one containing SKILL.md) into ~/.claude/skills/ for Claude Code, .agents/skills/ for Codex or .cursor/skills/ for Cursor. The agent picks it up automatically when a task matches its description.

Is the Esm skill free?

Yes. The repository is open source under the MIT license. The skill mentions an API key or token for an external service, which may need its own account.

Is Esm maintained?

The repository's most recent commit was on Oct 5, 2026. Its latest release is v2.72.0. appsgit only lists skills from repositories with a commit in the last six months.